AVISO IMPORTANTE


A partir del día 14 de junio de 2015, domingo, este blog dejará de ser actualizado como se ha venido haciendo hasta la fecha. La primera idea fue la de cerrar el blog, pero el deseo que que cuanto aquí se ha publicado pueda seguir siendo útil en el futuro, nos hace que mantengamos abierto el blog. Si tuviera alguna duda o quisiera hacer algún comentario, no tema hacerlo: seguiremos publicando cuantos comentarios se hagan y seguiremos contestando a las dudas que puedan surgir.
Gracias y hasta siempre.
Andrés Guerrero Serrano
-Homeópata-

martes, 4 de octubre de 2011

Mercurius solubilis: actions on macrophages.

(Extraído de PubMed.gov)

Homeopathy. 2011 Oct;100(4):228-36.

de Oliveira SM, de Oliveira CC, Abud AP, Guimarães Fde S, Di Bernardi RP, Coletto EL, Buchi Dde F.

Source

Laboratório de Estudos de Células Inflamatórias e Neoplásicas, Departamento de Biologia Celular, SCB, Universidade Federal do Paraná, Curitiba, PR, Brazil.

Abstract
BACKGROUND:

Macrophages play central roles in homeostasis as well as host defence in innate and acquired immunity, auto-immunity and immunopathology. Our research group has demonstrated the effects of highly diluted toxic substances in macrophages.

AIM:

To investigate if highly diluted Mercurius solubilis (Merc sol), can activate or modulate macrophage functions.

METHODS:

We evaluated the effects of Merc sol in the 6, 12, 30 and 200centesimal high dilutions (CH) potencies on mice peritoneal macrophages (in vitro and in vivo). Merc sol was added to mice's drinking water for 7days (in vivo treatment) and animals were euthanised and cells were collected. In vitro treatment was performed on macrophages and bone-marrow cell cultures.

RESULTS:

Macrophages showed activated morphology, both when Merc sol was added directly to the cell culture and to drinking water. The in vitro experiments showed enhanced morphological activation, increased interferon (IFN)γ release in the supernatant at lower dilutions and interleukin (IL)-4 production at higher dilutions. Increase in nitric oxide and decrease in superoxide (O(2)(-)) and hydrogen peroxide (H(2)O(2)) were also observed. In vivo treatment caused a decrease in O(2)(-) and increase in H(2)O(2) production by macrophages.

DISCUSSION:

Taken together, the results allow us to conclude that highly diluted Merc sol modulates reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokine secretion, which are central mediators of the immune system, wound healing and body homeostasis.

No hay comentarios:

Publicar un comentario